Retinol has dominated anti-aging skincare for decades, celebrated for its ability to boost skin cell turnover and diminish fine lines. But for women 35+, especially those experiencing hormonal changes, retinolʼs side effects—dryness, sensitivity, flaking—can outweigh the benefits¹.
The Retinol Dilemma after 35
Research shows midlife skin loses up to 30% of its collagen in the first 5 years post-menopause², necessitating effective renewal. However, over 50% of women experience increased skin reactivity during perimenopause and menopause³. Conventional retinol, while effective, often triggers redness and peeling⁴.
Enter Novoretin™: The Plant-Based Retinol Alternative
Novoretin™ is derived from Bidens pilosa extract, a botanical compound mimicking retinoic acid signaling without irritation⁵. In peer-reviewed, double-blind trials:
+31% increase in cell turnover at 28 days, matching prescription retinoids (5).
0% reported irritation at recommended dosage—no redness or flaking (5,6).
Suitable for sensitive and post-procedure skin, as confirmed by in-house and clinical testing (5,7).
Comparative Outcomes
| Traditional Retinol | Novoretin™ (Bidens pilosa) | |
|---|---|---|
| Cell turnover boost | 28–32% (4,5) | 31% (5) |
| Irritation (redness, dryness) | Common (4,6,7) | None reported (5,7) |
| Safe for sensitive skin | Rarely (4,6) | Yes (5,7) |
The Vyva Advantage
Vyvaʼs Cellular Radiance Serum harnesses Novoretin™ alongside gentle emollients, engineered for midlife skin seeking results without compromise. Dermatologist-developed, our formulas are free from parabens, silicones and harsh sulfates⁸, ensuring daily use is safe—even for sensitive, hormonally reactive skin.