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Cloned in sterile Swiss bioreactors, set into emulsions near Nice. Three serums kept in three bottles, because three full-dose actives destabilise each other in one. Start with your goal — we'll tell you which bottle, and when.
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Skin ages along three separate pathways: structural water loss, the enzymatic breakdown of your own retinoic acid, and localised pigment contrast. They cannot be addressed by one active, and they cannot be combined in one bottle at full clinical dose without destabilising each other. So we didn't.
At Mibelle Biochemistry, rare plant extremophiles are grown inside sterile bioreactors — polar mosses that survive where almost nothing does, and a Swiss apple known for refusing to wrinkle in storage. The cells are cultivated at peak potency. Nothing is stripped from a hillside.
The actives cross the border to be set into emulsions that are stable, cushioning and genuinely pleasant to wear. Switzerland decides what goes in. France decides how it feels.
Neither country would have made this alone.
Cleanse → Cellular Clarity → moisturiser → sunscreen, always
Cleanse → Renewal or Radiance → moisturiser. New to actives? Start every other night.
DAWN TO DUSK DUO
Clarity + RadianceOne price, from day one until you cancel.$117.90/month subscribed
BARE DUO
Clarity + RenewalOne price, from day one until you cancel.$120.95/month subscribed
THE COMPLETE SKIN RITUAL
All three serumsOne price, from day one until you cancel.$159.25/month subscribedEvery ritual: 60-day refund — opened or not, nothing to send back · free US shipping.

Supplier research by Mibelle Biochemistry — not independent trials, and not trials of the finished serums. Results refer to the appearance of skin.
No — and the difference is the reason there is no purge. Retinol adds a synthetic derivative your skin has to convert, and the conversion is what causes weeks of flaking. NovoRetin™ works the other way: it inhibits CYP26A1, the enzyme that degrades the retinoic acid your skin already makes. We add nothing. We stop something being destroyed. We also carry it at 3%, half again above the concentration its studies used.
Because polynucleotides hold water in a way humectants sitting on the surface cannot. Ours are salmon-roe derived, fragmented to around 110 kDa — inside the range the research works in — at 5%, the highest concentration the supplier has tested. And because it is animal-derived we say so plainly on the front: contains salmon-derived DNA, not suitable for fish allergies, not vegan. We would rather lose the sale than bury that.
Those work by injuring the skin on purpose and letting it heal. That is a legitimate choice, with downtime and a clinic bill attached. This is the other route: no wound, no recovery, actives at or above their studied concentrations, used at home on a Tuesday. We are not claiming to replace a dermatologist. We are claiming to be worth using between visits.
France. The emulsions, the texture, the stability.
Actives cultivated at Mibelle Biochemistry, Buchs.
Heroes at or above their studied concentration. Texturizers printed too.
Chios mastic — a cultivation practice inscribed in 2014.
Composition patents, not marketing language.
Sixty days from delivery, opened or not. Keep it — there is nothing to send back.
Every one of these is a fact you can verify without us.