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VyVa is a cellular wellness brand for adults 35+. We pair three patented, clinically studied supplement actives with three French-formulated cellular skincare serums — built around the biology that shifts after 35. Every formula is anchored in published research, batch-tested by an independent ISO-accredited laboratory, and transparently labeled.

VyVa is built around true inside-out integration. Every supplement and every serum is formulated to complement the others as one cellular wellness system. Where many brands sell one thing—supplements or skincare—VyVa is designed around the principle that cellular biology doesn't stop at the skin's surface. Our active ingredients are patented, clinically studied, and disclosed at their actual concentrations.

• Cellular Nutrition: Targeted supplements with patented actives for joint health, energy, and skin radiance
• Cellular Renewal: Clean, dermatologist-developed skincare with natural ingredients and scientific actives

Q-Actin® is a patented cucumber extract (US Patent 9,326,977 B2) studied in three peer-reviewed clinical trials for joint comfort and mobility.

In a 180-day randomized double-blind trial of 122 adults aged 40–75 with moderate knee osteoarthritis, Q-Actin® reduced WOMAC joint scores by 70.3% — compared to 33.7% for 2,700 mg of glucosamine-chondroitin (Nash et al., 2018, Clinical Interventions in Aging, PMC6207263). A separate 60-day placebo-controlled trial published in Cureus (2025) reported 31.79% WOMAC improvement at Day 60. Individual results may vary.

Users report noticing easier movement and improved joint comfort, with full benefits building over 4–8 weeks of consistent use. Clinical study data shows meaningful improvement by Day 30.†

Yes. Vflex uses clinically studied doses and is manufactured in cGMP-certified facilities with third-party testing for purity and potency.

You can, but most people don't need to. Vflex is designed as a low-dose, standalone solution. If you're on prescription medications, consult your healthcare provider.

Those who are pregnant, nursing, have cucumber allergies, or medical conditions should consult a physician first.

Yes. Unlike glucosamine (which is typically derived from shellfish), Q-Actin® is extracted from cucumber. Vflex is safe for individuals with shellfish allergies.

Ioniplex® is a patented fulvic ionic mineral complex delivering more than 65 trace minerals in ionic form. It's designed to support cellular mineral nutrition — the foundation for skin, hair, nail, and connective tissue maintenance.

Ioniplex® holds two issued US patents (8,709,497 + 8,927,031) and has been evaluated in a six-week randomized double-blind placebo-controlled clinical study on nail condition (Boisits 2009). Manufacturer laboratory data describes effects on cellular collagen pathways and mineral bioavailability. Independent peer-reviewed human clinical trials on Ioniplex® specifically are an emerging area of research.

Texture improvements often appear by week 8, with continued gains through 12 weeks.

Yes. Vegan, sugar-free, non-GMO, and free from animal collagen, dairy, soy, and gluten.

MitoPrime® is a high-purity form of L-ergothioneine — an amino acid your body actively conserves through a dedicated cellular transporter (OCTN1).

Ergothioneine has been proposed as a putative longevity-vitamin candidate by Bruce Ames (PNAS, 2018) — a hypothesis paper, not an established conclusion — and is studied for its role in antioxidant defense, particularly in cellular environments where common antioxidants like glutathione are less stable. Individual responses may vary.

Users report a sense of improved energy and mental sharpness after consistent use, typically within 2–4 weeks. Individual results may vary.†

Yes. MitoV+ is specifically formulated for adults 35+ and contains no stimulants. As with any supplement, consult your healthcare provider if you have a medical condition or take medications. †

MitoV+ is stimulant-free. Rather than relying on caffeine or guarana for a temporary lift, MitoPrime® L-ergothioneine works at the cellular level by supporting antioxidant pathways and the mitochondrial environment. There are no crashes because there's no spike to crash from.

Yes. All VyVa supplements are designed to work synergistically. Popular combinations include Vflex + Vioni+ for joint and skin support, or all three for complete cellular wellness.

Take our 1-minute personalized quiz, or start with our System Bundle for comprehensive cellular support.

Yes, all formulas complement existing wellness routines. Consult your healthcare provider if taking prescription medications.

No. All VyVa supplements are stimulant-free and athlete-friendly.

"Clinical Nature. Visible Results." Our dermatologist-developed formulas blend cutting-edge science with nature's best, specifically designed for adults 35+ with sensitive skin.

VyVa serums are formulated with sensitive skin in mind — dermatologist-tested and free from parabens, silicones, and harsh sulfates. We always recommend a patch test when introducing any new active product. †

For first-time users, try our Cellular Renewal Serum for overall skin health, or take our skincare quiz for personalized recommendations.

Users report noticing improvement in the appearance of skin texture and hydration within the first few weeks, with visible brightening and firming benefits typically appearing over 4–6 weeks of consistent use. Individual results may vary.†

Absolutely. Apply after cleansing and before moisturizer. Our pH-balanced, non-comedogenic formulas enhance your existing routine.

Cellular Clarity Serum and Cellular Radiance Night Serum are both vegan and suitable for plant-based routines.

Cellular Renewal Serum is not vegan. It contains a salmon-derived DNA polynucleotide complex (Sederma DNA Gel™ PH, salmon soft-roe origin). We do not recommend Cellular Renewal Serum for individuals with fish or seafood allergies. Cellular Renewal Serum is a topical cosmetic — not in the injectable PDRN category. All ingredients are disclosed at their actual concentrations on our Ingredients page.

Start by alternating nights and keep the rest of your routine simple. Always use SPF during the day.

Pat a thin layer along the orbital bone if well-tolerated. Avoid direct contact with eyes.

Yes. Allow full absorption, then apply SPF and makeup as usual.

VyVa serums are formulated for daily use as part of your personal skincare routine. If you are undergoing professional treatments, consult your skincare professional regarding the appropriate timing for introducing new products

Start gradually, especially with active ingredients. Patch test first if you have sensitive skin. For supplements, take with food and water for best absorption.

Mild digestive discomfort may occur when starting new supplements—take with food. For skincare, reduce frequency if irritation occurs. Discontinue and consult a healthcare provider if concerns persist.

Consult your physician before use during pregnancy or nursing.

We offer a 30-day Feel-Good Guarantee on supplements and 30-day satisfaction guarantee on skincare. If you're not completely satisfied, contact us for a full refund—no return required.

Orders ship within 24–48 business hours from our fulfillment center. You'll receive a tracking link by email as soon as your order is on its way. Standard delivery within the US typically takes 3–5 business days. For international shipping or expedited options, see your cart at checkout for available carriers and rates to your destination.

Contact our customer care team. We stand behind our products and will work with you to find the right solution or provide a full refund.

Yes. VyVa never tests on animals. Our skincare is manufactured in France under EU Cosmetics Regulation 1223/2009, which prohibits animal testing for cosmetic ingredients and finished products.

Take our personalized quiz to discover products tailored to your needs, or consider our System Bundle for comprehensive cellular wellness support.

We recommend 30 days for supplements and 4-6 weeks for skincare to experience full benefits, though many customers notice improvements much sooner.

Yes. Our wellness specialists are available to help you choose the right products and optimize your cellular wellness routine.