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30 ml — roughly two monthsVegan · contains mastic gumFormulated in FranceFull INCI published
CELLULAR RADIANCE · NIGHT SERUM · SMOOTHNESSNovoRetin™ at 3% — 1.5× the studied level
Surface renewal without retinol.
NovoRetin™ is not retinol and not a retinoid — it works with the retinoic acid your skin already makes. In its maker’s split-face study, 3D scanning thirty minutes after a single application recorded the appearance of wrinkle depth down 14.0% against placebo. Over 28 days at 2%, skin density improved 13.8% against placebo. Ours is 3%.
3%NovoRetin™ — 1.5× studied
2%the level its studies used
30 mlroughly two months
−14.0%wrinkle-depth look, at 30 minutes
60-day refund — opened or not, nothing to send back · Free US shipping · Full INCI published
- Not retinol. Its own ingredient — NovoRetin™ at 3%
- Top of its 2–3% range — 1.5× the level its maker studied
- Mastic gum is a documented contact allergen — patch test 48 hours first
- Night use only · vegan · made in France
Night. Build up if you’re new to actives.
Cleanse
Clean, dry skin.
Apply
A few drops before moisturiser. New to evening actives? Start every other night.
Day after
Sunscreen in the morning, always — standard practice with any renewal active.
WHY IT WORKS
Thirty minutes. Then look again.
Most night serums ask for six weeks of faith. In its maker’s split-face study on 22 women aged 42 to 65, a single application of NovoRetin™ was measured by PRIMOS 3D structured-light scanning exactly thirty minutes later: against placebo, the appearance of wrinkle depth was down 14.0%, wrinkle length down 13.7% and roughness down 6.4%. 82% of the volunteers said the eye contour looked immediately smoothed and lifted.
Not a blur and not a filler — the geometry was scanned. It isn’t retinol either: instead of adding a retinoid, it works with the retinoic acid your skin already makes, and in its studies hydration went up rather than down.
Over 28 days at 2%, skin density improved 13.8% against placebo (Dermalab® ultrasound, n=18 women aged 42 to 70), while skin elasticity improved 20.4% against their own starting condition (Cutometer) — we publish which comparison each number came from, because they are not the same claim. Pore count fell 30.3% inside two weeks.
Ours is 3%, half again above the studied level. Made in Carros, France. Results refer to the appearance of skin.
THE STUDY MOST INGREDIENT FILES DO NOT HAVE
Radiance and evenness of tone, measured on seventy-two women.
Plenty of “natural retinol alternatives” are studied on one narrow group and then sold to everyone. NovoRetin™ went through a separate 28-day split-face study against placebo on 72 women with Fitzpatrick IV–V skin, measuring brightness and evenness of tone.
88% showed improved brightness, against 33% on placebo.
Glow and evenness, measured on skin that most ingredient files never include. Results refer to the appearance of skin.
THE QUESTION EVERYONE ASKS
“Isn’t bakuchiol the plant retinol alternative?”
Bakuchiol is a single molecule resting essentially on one flagship trial from 2019, and the category has been repeating it ever since. NovoRetin™ has seven distinct human studies behind it, and is harvested as mastic resin tears on Chios — a cultivation practice inscribed on UNESCO’s Intangible Cultural Heritage list in 2014, under Protected Designation of Origin.
It is not offered as a substitute for anything. It is its own ingredient, with its own file.
Seven studies against one is not a claim about which works better. It is a statement about how much is known.
WHAT'S INSIDE
A different route to surface renewal.
Retinol asks for an adjustment period and careful layering. NovoRetin™ takes a different route — raising the retinoic acid your skin already produces — with the allergen it carries named on the front.
NovoRetin™ — 3% — mastic-tree derived; half again above the studied 2% level
The allergen, named — mastic gum is a documented contact allergen — patch test first
Everything else — sea buckthorn, licorice root, hyaluronic acid — base conditioners at trace levels. Named on the label, claimed nowhere.
The full label
Thirty minutes. Then look again.
Most night serums ask for six weeks of faith. In its maker's split-face study on 22 women aged 42 to 65, a single application of NovoRetin™ was measured by PRIMOS 3D structured-light scanning exactly thirty minutes later: against placebo, the appearance of wrinkle depth was down 14.0%, wrinkle length down 13.7% and roughness down 6.4%. 82% of the volunteers said the eye contour looked immediately smoothed and lifted. Not a blur and not a filler — the geometry was scanned.
It is not retinol, and that is the point rather than the apology. Retinol adds a retinoid to your skin, with the dryness that comes with it. NovoRetin™, derived from mastic gum, raises the retinoic acid your skin already makes — and in its maker's studies it increased hydration instead of causing dryness.
Over 28 days at 2%, skin density improved 13.8% against placebo (Dermalab® ultrasound, n=18 women aged 42 to 70), while skin elasticity improved 20.4% against their own starting condition (Cutometer). We publish which comparison each number came from, because they are not the same claim. Pore count fell 30.3% and pore volume 41.7% within two weeks.
A separate 28-day split-face study against placebo ran on 72 women with Fitzpatrick IV–V skin, measuring brightness and evenness of tone: 88% showed improved brightness against 33% on placebo.
We use it at 3% — 1.5× the studied concentration. Everything else in the bottle is base: sea buckthorn, licorice and hyaluronic acid sit at trace levels, and we claim nothing for them. Applied in the evening. Made in Carros, France.
The research is Mibelle Biochemistry's own, into the ingredient rather than into this finished serum.
Contains mastic gum, a documented contact allergen. Patch test on the inner arm and wait 48 hours before first use; stop if you react. For external use only. Avoid the eye area. Use broad-spectrum SPF 30+ each morning. Results refer to the appearance of skin and vary between individuals.
THE FORMULA, PRINTED
Every active, and how much of it is in the bottle.
Ingredient lists use INCI names, which is why a hero active can hide inside words like “pistacia lentiscus (mastic) gum” or “hippophae rhamnoides fruit extract”. So here is the plain version: what we call each active, and how much of it is in the finished serum.
Supplier actives are studied and sold as one complete material, so “3% NovoRetin™” means 3% of the material its studies used — and that is the number we hold ourselves to.
| What we call it | How much is in the serum |
|---|---|
| NovoRetin™ | 3.000% |
| Vitamin tree (sea buckthorn) a botanical, not a dosed active | 2.000% |
Kept deliberately small
Base conditioners, stabilisers and carriers. Present in the bottle, named here, and claimed nowhere.
- Licorice rootglycyrrhiza glabra root extract
- Hyaluronic complexfour hyaluronate weights, blended
- Lipomoistcarrageenan-based conditioning blend
The complete INCI list, exactly as it appears on the carton
Below a concentration of 1%, ingredients may be listed in any order — a standard INCI convention.
aqua (water), glycerin, polysorbate 20, pistacia lentiscus (mastic) gum, hippophae rhamnoides fruit extract, glycyrrhiza glabra (licorice) root extract, sodium acetylated hyaluronate, sodium hyaluronate, sodium hyaluronate crosspolymer, hydrolyzed sodium hyaluronate, glucose, chondrus crispus (carrageenan) extract, 1,2-hexanediol, hydroxyethylcellulose, propanediol, hydroxyacetophenone, caprylic/capric triglyceride, butylene glycol, lecithin, caprylhydroxamic acid, hexanediol, sodium nitrate, glyceryl caprylate/caprate, disodium phosphate, sodium phosphate, ethylhexylglycerin, polysorbate 60, xanthan gum, caprylyl glycol, phenoxyethanol, pentylene glycol
Discontinue use and consult a physician if irritation or unexpected reaction occurs. Not recommended for individuals sensitive to any ingredient in this product.
Source: the INCI declaration printed on the carton.
WHERE THE EVIDENCE STANDS
The maker’s numbers, and the allergen, both on the front.
Evidence tier
Supplier research — Mibelle Biochemistry’s ingredient studies, not independent trials of this finished serum.
The key numbers
At 30 minutes after one application, against placebo: appearance of wrinkle depth −14.0%, length −13.7%, roughness −6.4% (PRIMOS 3D scanning, n=22). At 28 days at 2%: skin density +13.8% against placebo; skin elasticity +20.4% against baseline. Ours is 3% — above, and printed.
What we claim
Appearance of smoothness and surface renewal.
Published with your order
Full INCI, allergens first: mastic gum — patch test 48 hours.
Where a number is measured against placebo we say so, and where it is measured against the volunteer’s own starting condition we say that instead. They are not the same claim. Skin is individual — we will not print a date for your face.
Things we decided not to do.
- No calling it retinol. It isn’t — and the difference is the point.
- No hiding the allergen. Mastic gum, named before you buy.
- No before-and-after photographs. They prove nothing.
- No reviews yet. When real customers exist we’ll publish what they actually said.
Everything on this page can be checked. That's the entire pitch.
FAQ
- Is it a retinoid?
- No. NovoRetin™ supports the retinoic acid your skin already makes — a different mechanism, without the retinoid adjustment period.
- Can I use it with acids?
- Alternate nights at first and keep the routine simple. Sunscreen every morning.
- Is it vegan?
- Yes. It contains mastic gum — patch test 48 hours before first use.
- When will I see something?
- In the maker’s testing, the appearance of wrinkle depth and roughness was measurably changed thirty minutes after one application; the bigger numbers took 28 days. Beyond what the studies measured, no dates — anyone who promises one is guessing.
THE GUARANTEE
Sixty days. Then decide.
If it isn’t for you, tell us and we’ll refund it — opened or not. Keep the bottle; there’s nothing to send back. Sixty days is a refund window, not a results window.
Contains mastic gum. Patch test 48 hours before first use.
60-day refund — opened or not, nothing to send back · Free US shipping · Full INCI published
COMPLETE THE RITUAL
Where this step fits.
Dawn to Dusk DuoClarity in the morning, Radiance at night.One price, from day one until you cancel.$117.90/month subscribed
The Complete Skin RitualAll three serums — the complete morning-to-night routine.One price, from day one until you cancel.$159.25/month subscribedFor external use only. Avoid the eye area. Patch test 48 hours before first use. Discontinue use if irritation occurs. Use sunscreen when exposed to sunlight. Keep out of reach of children. Results refer to the appearance of skin. Individual results may vary. NovoRetin is a registered trademark of Mibelle AG.