The cosmetic research behind our plant retinol alternative
Five actives. One night-only ritual. Designed for adults who want retinoid-adjacent benefits with a calmer tolerance profile. Locked formula FOR.25.185.01. Manufactured in France.
Important. Cellular Radiance Night Serum is a night-only cosmetic serum. Broad-spectrum SPF the next morning is essential when using any retinoid-pathway active. This is a cosmetic — not a drug. We do not claim it works like prescription retinoids. We do not claim "tretinoin alternative" or "retinol-level results."
NovoRetin™ — Plant Retinol Alternative
NovoRetin: The Natural Retinol Alternative + Retinol Benefits with a Natural and Safe Alternative
Personal Care Magazine, July 2022 (Mibelle Biochemistry technical publication).
HAPPI Magazine, June 2024 (Mibelle Biochemistry technical publication).
NovoRetin™ is a Mibelle Biochemistry cosmetic active derived from Pistacia lentiscus (mastic) gum, delivered in a caprylic/capric triglyceride matrix. Mibelle's cosmetic ingredient research documents NovoRetin™ as supporting the skin's own retinoid signaling — without introducing exogenous retinoic acid.
Important context. Mibelle's published mechanism reference describes NovoRetin's effect on the CYP26A1 enzyme pathway (which regulates the body's own retinoic acid). Because that mechanism reference can be interpreted as drug-tier, we keep it on this science page only — never in ads, never in PDP hero copy. Consumer-facing claims for Cellular Radiance describe cosmetic appearance benefits: smoother-looking, firmer-looking, more rested-looking skin.
Read Personal Care Magazine 2022 →Hymagic™ 4D — Four Forms of HA in One Ingredient
Hymagic™ 4D Four-Form Hyaluronic Acid System
Bloomage Biotech (the world's largest cosmetic-grade hyaluronic acid producer) developed Hymagic™ 4D to deliver four molecular weights of hyaluronic acid in one ingredient:
- Sodium hyaluronate crosspolymer — long-lasting surface hydration film
- Sodium hyaluronate — mid-MW dermal plumping (the workhorse)
- Sodium acetylated hyaluronate — enhanced affinity, longer-staying
- Hydrolyzed sodium hyaluronate — small-MW deeper-reaching cosmetic hydration
Vitamin Tree (Hippophae rhamnoides) — Sea Buckthorn
Hippophae rhamnoides Fruit Extract (DKSH HD2 / Vitamin Tree)
Sea buckthorn berry extract has a deep history in skin care for its carotenoid and omega-7 content. Used in Cellular Radiance Night Serum at 2% raw, delivering Hippophae rhamnoides fruit extract at 0.006% in the finished serum.
Lipomoist™ 2013 + Viapure™ Licorice White
Lipomoist™ 2013 (Lipotec / Lubrizol) + Viapure™ Licorice White (LSC / SACI-CFPA)
Lipomoist™ 2013 — peptide-mimetic hydration complex from Lipotec / Lubrizol. Designed to support 24-hour cosmetic hydration.
Viapure™ Licorice White — Glycyrrhiza glabra root extract. A traditional botanical with cosmetic ingredient research supporting its use for soothing and tone-evening.
What's NOT in the Formula
Cellular Radiance Night Serum does not contain:
- Bakuchiol. Despite some category positioning, bakuchiol is not in our locked formula. Our retinol alternative is NovoRetin™ — a different active.
- Retinol or retinoic acid. NovoRetin™ supports the skin's own retinoid signaling without introducing exogenous retinoic acid.
- Hydroquinone. Hydroquinone is a regulated skin-lightening drug; it is not in our cosmetic formula.
Manufacturing & Regulatory
Manufactured in France by EC&P (Europe Cosmétiques et Parfums)
Locked formula FOR.25.185.01, version 01, dated 25 August 2025. Manufactured under EU Cosmetics Regulation 1223/2009. FDA cosmetic facility registration: FEI 3008182565.
