Full INCI published, all three30 ml each — roughly two monthsFormulated in FranceContains soy, fish and mastic gum — stated before you buy

THE COMPLETE SKIN RITUAL · THREE SERUMS · MORNING AND NIGHTSwiss actives — Mibelle AG · full INCI on all three

One for the morning. Two for the night. The whole routine.

Cellular Clarity every morning for the appearance of even tone. Cellular Renewal and Cellular Radiance at night, alternating — for the look of firmness and smoothness. Every active named, every concentration printed — including the one below its studied level.

3serums — the complete routine

4%Delentigo™ — its studied level

3%NovoRetin™ — 1.5× the studied level

2%MossCellTec™ No. 1 — its studied level

60-day refund — opened or not, nothing to send back · Free US shipping · Full ingredient list on all three

Firmness — Cellular Renewal for firmer, more resilient-looking skin
Tone — Cellular Clarity to even and brighten the look of skin
Texture — Cellular Radiance to smooth and renew the look overnight
The full system — brighten + firm by day, renew by night. Best value of the line

Swiss actives — Mibelle AGSpot pigment −26% at eight weeks — contrast gap closed by roughly halfWrinkle-depth look −14.0% vs placebo, thirty minutes after one applicationCrow's-feet wrinkle-depth look −15% vs placebo at 28 daysEvery concentration printed — including the one below its studied level

One in the morning. One at night.

Morning

Cellular Clarity, after cleansing, before moisturiser. Then sunscreen, always.

Night

Cellular Renewal or Cellular Radiance, after cleansing, before moisturiser — one serum per night, alternating.

New to an evening active?

Start every other night and build up.

Three serums, three jobs, one routine.

01 · Morning

Cellular Clarity

Every brightener makes the spot lighter. This one closes the gap. Delentigo™ at 4% — its studied concentration.

Delentigo™ 4%MossCellTec™ 2%Vitamin CKADHA

Contains soy. Vegan.

02 · Night

Cellular Renewal

Skin that looks rested and full. Salmon polynucleotides at 5% with MossCellTec™ at its studied 2%.

Salmon DNA 5%MossCellTec™ 2%PhytoCellTec™ 1%BiotinHA

Contains fish. Not suitable for vegans or anyone with a fish allergy.

03 · Night

Cellular Radiance

Surface renewal without retinol. NovoRetin™ at 3% with four-weight hyaluronic acid.

NovoRetin™ 3%Sea BuckthornLicorice Root4-Weight HA

Contains mastic gum, a documented contact allergen — patch test first.

Even tone in the morning. Firmness and smoothness at night. Three serums rather than one bottle claiming to do everything.

THREE SERUMS, THREE DIFFERENT JOBS

What each one changes

These are the results the ingredient makers measured, at the concentrations we use. Skin is individual and we will not give you a date — but this is the timescale the research ran on.

Before you start: Cellular Renewal contains fish — the polynucleotide complex is salmon-derived, so it is not vegan and not suitable for anyone with a fish allergy. Cellular Clarity contains soy (genistein) and 0.34% alcohol. Cellular Radiance contains mastic gum, a documented contact allergen. Patch test each serum on the inner arm and wait a full 48 hours before first use, stop if you react, and introduce them one at a time. The research is Mibelle Biochemistry's own, into these ingredients rather than into the finished VyVa serums.

Morning · Cellular Clarity — every brightener makes the spot lighter; this one closes the gap Most brighteners act everywhere they are applied, so the spot fades and your skin tone fades with it. Delentigo™ was built to close the gap instead. In its maker's eight-week study on 12 women aged 40 to 77, the pigment reading in treated age spots fell 26% while the normally pigmented skin around them moved 16.5% — closing the visible contrast between the two by roughly half. At four weeks in the same programme, the melanin index of treated spots was down 6.2% against placebo while normally pigmented skin was unchanged. At 4% — the concentration those studies used.

Night · Cellular Renewal — firmer-looking where it creases first The corner of the eye. MossCellTec™ No. 1 sits here at 2%, exactly its studied level: measured against placebo over 28 days, the appearance of crow's-feet wrinkle depth fell 15%. In the same bottle, PhytoCellTec™ Malus Domestica — in its maker's four-week trial with 20 subjects, a 2% cream reduced crow's-feet wrinkle depth by 8% at two weeks and 15% at four, measured by the PRIMOS system. That study ran at 2%; this serum carries 1%, which we print rather than round away. And salmon-derived polynucleotides at 5%, the maximum concentration their supplier has tested.

Night · Cellular Radiance — something changes in the first thirty minutes In its maker's split-face study on 22 women aged 42 to 65, PRIMOS 3D scanning exactly thirty minutes after a single application recorded the appearance of wrinkle depth down 14.0% against placebo, wrinkle length down 13.7% and roughness down 6.4% — and 82% said the eye contour looked immediately smoothed and lifted. Over 28 days at 2%, skin density improved 13.8% against placebo, while skin elasticity improved 20.4% against their own starting condition; pore count fell 30.3% within two weeks. We publish which comparison each number came from, because they are not the same claim. We use it at 3% — 1.5× that concentration.

WHY YOUR LAST BRIGHTENER DID NOT WORK

Your age spots are not one pigment. They are two.

If you have tried a brightener and the spot came back, this is probably why. Most of them address one of the two pigments in an age spot, and they do it everywhere they are applied, not just where the spot is.

The pigment from sun

Melanin

Your skin makes it in response to UV light. It is the brown pigment most brighteners are built to target — but they act on every cell they touch, so the skin around the spot lightens with it.

The pigment from time

Lipofuscin

A wear-and-tear pigment that accumulates inside skin cells over decades. It gives age spots their golden undertone, and almost no brightener on the shelf is formulated to address it at all.

A spot is not dark. It is darker — and the gap is the only reason you can see it. In Delentigo™'s eight-week study the treated spots fell 26% while the skin around them moved 16.5%, closing that gap by roughly half.

Age spots contain both melanin and lipofuscin, well documented in dermatological literature. The selectivity claim is based on Mibelle Biochemistry's research into the ingredient — supplier research, not independent trials, and not trials of the finished VyVa serum. Results refer to the appearance of skin.

THE QUESTION A THREE-SERUM ROUTINE CREATES

Two night serums. One night. So which one?

Either. Just not both at once.

Renewal and Radiance are both evening serums, and they are doing different jobs — one works on the appearance of firmness and skin quality, the other on smoothness and surface renewal. Use one per night and alternate them.

Three reasons, and none of them is scarcity. Each active was studied on its own, at its own concentration, so alternating is the only pattern that matches how the evidence was generated. Layering two renewal-focused actives raises the chance of irritation without any evidence of added benefit. And if your skin does react, alternating means you know which bottle to stop.

Clarity is the morning step and does not compete with either. Sunscreen over it, every day.

The three VyVa serums — Cellular Clarity, Cellular Renewal and Cellular Radiance

What you actually get

Three full-size serums. Every concentration published.

Delentigo™ at its studied 4%. NovoRetin™ at 3%, half again above its studied level. MossCellTec™ at its studied 2%, in two of the three bottles. Salmon polynucleotides at 5%, the top of their supplier's tested range. And PhytoCellTec™ at 1% where its study ran at 2% — printed rather than rounded away.

MOSSCELLTEC™ NO. 1 · 2% · THE ACTIVE THAT REPEATS

One active runs through two of these bottles. At its studied level.

Moss survives what would kill a garden, and the active is built around that idea: skin that keeps up with change rather than skin being corrected. It is one of the very few cosmetic actives with published work on the health of the cell nucleus.

That was tested in the most hostile real-world conditions available — 23 women through a Seoul summer, moving repeatedly between humid outdoor heat and dry air-conditioned offices. Every one of the 23 recorded a significant increase in skin hydration on the treated side within 14 days, and 91% recorded lower water loss. That is a responder rate inside one clinical cohort, not a guarantee.

Included at the level its maker recommends, not a dusting.

Photobioreactor-grown No field, no crop, no season — a Swiss moss cell culture rather than a harvest.

2% — its studied level, exactly Measured against placebo over 28 days, the appearance of crow's-feet wrinkle depth fell 15%.

In two of the three bottles Cellular Clarity and Cellular Renewal. Not in Radiance — we say which, rather than implying all three.

Most brands name the ingredient. We match the dose.

Row	Cellular Clarity	Cellular Renewal	Cellular Radiance
Key active	Delentigo™ at 4%	Salmon polynucleotides at 5% · MossCellTec™ at 2% · PhytoCellTec™ at 1%	NovoRetin™ at 3%
Its study used	4% — match	5% is the supplier's maximum tested and MossCellTec matches at 2%; PhytoCellTec's study ran at 2% and ours is 1% — printed, not rounded away	2% — ours is 1.5× the studied level, printed here
Also in the bottle	MossCellTec™ No. 1 at 2% — the maker's level	same	Sea buckthorn, licorice root and a four-weight hyaluronic complex — base conditioners, claimed nowhere
What we claim	Appearance of even tone	Appearance of firmness and skin quality	Appearance of smoothness and surface renewal
Allergens, stated upfront	Soy	Fish — not vegan	Mastic gum — patch test first

The research belongs to the ingredients and was run by Mibelle Biochemistry, their Swiss maker — supplier research, not independent trials, and not trials of these finished serums. One number here does not flatter us. It is printed anyway.

Things we decided not to do.

No before-and-after photographs. Shot in different light, they prove nothing.
No promise of when you'll notice something. Nobody can honestly give you a date.
No hiding the allergens. Clarity contains soy, Renewal contains fish, Radiance contains mastic gum — all stated here, before you buy.
No proprietary complexes. Named actives, full list published.
No pretending one active is in all three. MossCellTec™ is in two of the bottles. We say which.

Everything on this page can be checked. That's the entire pitch.

FAQ

How do I use all three?: Clarity in the morning, under sunscreen. At night, one serum per night — alternate Renewal and Radiance.
Can I use both night serums on the same night?: We would not. Each active was studied on its own, layering two renewal-focused actives raises the chance of irritation with no evidence of added benefit, and if you do react, alternating tells you which bottle to stop.
Are they vegan?: Clarity and Radiance are. Renewal is not — it contains salmon-derived DNA. If you have a fish allergy, Renewal is not for you.
How long does each bottle last?: 30 ml each. Used as directed, the trio covers roughly a two-month routine.
When will I see something?: No date. Anyone who gives you one is guessing.

THE SHAPE OF THE ROUTINE

One in the morning. Two at night, alternating.

Cellular Clarity every morning, under sunscreen. Then Cellular Renewal or Cellular Radiance at night — one per night, never both, because each was studied on its own and alternating tells you which bottle did what. Three bottles, 30 ml each, roughly two months of the full routine.

The Complete Skin Ritual — all three VyVa serums

THE GUARANTEE

Sixty days. Then decide.

If it isn’t for you, tell us and we’ll refund it — opened or not. Keep all three; there’s nothing to send back. Sixty days is a refund window, not a results window.

Contains soy, fish and mastic gum. Patch test 48 hours before first use.

60-day refund — opened or not, nothing to send back · Free US shipping · Full ingredient list on all three

COMPLETE THE SYSTEM

Where this ritual leads.

The Complete Cellular RitualAll three supplements — two in the morning, one before bed.One price, from day one until you cancel.Subscribed: $98.90/month~~$157.00~~$109.90 one-time Save $11.00 every monthSEE THE RITUAL →

The Defence RitualMitoV+ and Cellular Clarity — one you take, one you apply, both in the morning.One price, from day one until you cancel.Subscribed: $92.15/month~~$128.00~~$102.40 one-time Save $10.25 every monthSEE THE RITUAL →

The Foundation RitualVioni+ in the morning, Cellular Renewal at night — the simplest way in.One price, from day one until you cancel.Subscribed: $102.95/month~~$143.00~~$114.40 one-time Save $11.45 every monthSEE THE RITUAL →

The Journal

ALL ARTICLES

Skincare How to Layer Serums: An AM/PM Routine After 35

Skincare Skin Firmness After 35: What Actually Helps the Look

Skincare Polynucleotides in Skincare: Salmon DNA, Explained

Inside + Out Glow From Within: Supplements for Glowing Skin

For external use only. Avoid the eye area. Patch test 48 hours before first use. Discontinue use if irritation occurs. Use sunscreen when exposed to sunlight. Keep out of reach of children. Results refer to the appearance of skin. Individual results may vary. Delentigo, PhytoCellTec, NovoRetin and MossCellTec are registered trademarks of Mibelle AG.