Cellular Renewal Serum for Fine Lines & Firmness 35+

Cellular Renewal Serum

$89.00

Intensive Renewal That Feels Gentle on Skin

1 Bottle $89.00

2 Bottle $160.00 $178.00 Save $18.00

3 Bottle $227.00 $267.00 Save $40.00

Launch Special: Use code VYVA20 for extra 20% off (first 500 customers only)

Plant stem cells and a salmon-derived DNA complex for the look of firmer, smoother skin in one advanced serum.

Key Active Ingredients

Ingredient	Function
Malus Domestica Fruit Cell Culture Extract (PhytoCellTec™)	Apple-derived plant stem cell extract; helps support the look of a youthful, resilient complexion
Salmon-Derived DNA	A salmon-derived DNA polynucleotide complex in a hyaluronic-acid gel base, formulated to support the appearance of firmer, more resilient-looking skin
Biotin	B-vitamin; helps support skin's moisture and a healthy-looking surface
Sodium Hyaluronate	Hyaluronic acid; deep hydration, plumping, barrier support

Full Ingredient List (INCI)

Aqua (Water), Glycerin, Isomalt, Polysorbate 20, 1,2-Hexanediol, Hydroxyethylcellulose, Propanediol, Hydroxyacetophenone, DNA, Malus Domestica Fruit Cell Culture Extract, Caprylhydroxamic Acid, Phenoxyethanol, Sodium Nitrate, Carbomer, Xanthan Gum, Potassium Sorbate, Disodium Phosphate, Sodium Phosphate, Sodium Benzoate, Sodium Hyaluronate, Sodium Metabisulfite, Polysorbate 60, Phytol, Biotin.

Individual results may vary. For external use only. Avoid contact with eyes. Discontinue use and consult a physician if irritation occurs. Not recommended for individuals sensitive to any ingredient in this product. Keep out of reach of children.

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Third-Party Tested for Purity & Potency

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Swiss apple plant cell culture extract, designed to support a youthful-looking complexion

Formulated with a salmon-derived DNA polynucleotide complex

Helps visibly smooth the look of fine lines

Gentle enough for AM/PM use

Benefits of Cellular Renewal Serum

Plant Cell Culture Extract

PhytoCellTec™ Malus Domestica, a Swiss apple plant cell culture extract designed to support a youthful, resilient-looking complexion.

Salmon-Derived DNA Complex

A salmon-derived DNA polynucleotide complex formulated to support the appearance of firmer, more resilient-looking skin.

Barrier-Strengthening Hydration

Multi-weight hyaluronic acid and antioxidants help support the look of a hydrated, resilient complexion.

Research-Backed Results

Studies conducted with PhytoCellTec™ and Marine DNA extract

Outcome

Stem cell colony efficiency

New tissue formation

Anti-wrinkle effects

Skin density

Surface smoothness

Eye contour wrinkles

Result

Maintained vitality

Supported renewal

Crow's feet improvement

Increased measurements

Improved texture

Reduced depth

Study Type

In vitro studies

3D epidermis models

In vivo testing

Clinical studies

Consumer studies

Clinical measurements

In a 28-day study of the active ingredient at the studied concentration, researchers observed increased firmness and dermal density. Individual results may vary

Comparison Table

How VyVa Renewal Serum Outperforms:

Feature

VyVa Renewal

Retinol Seruns

Peptide Serums

Vitamin C Serums

Plant Cell Culture Extract

✅ PhytoCellTec™

❌ No stem cell support

❌ Limited renewal

❌ Antioxidant only

Polynucleotide Complex

✅ Salmon Derived DNA

❌ Cellular turnover only

⚠️ Signal peptides

❌ No regeneration

Gentle for Sensitive Skin

✅ Barrier-friendly

❌ Often irritating

✅ Generally gentle

⚠️ Can irritate

AM/PM Usage

✅ Both suitable

❌ PM only

✅ Both suitable

⚠️ AM with caution

Eye Area Safe

✅ Gentle enough

❌ Too harsh

✅ Usually safe

⚠️ May sting

Post-Procedure Use

✅ Clinician-approved

❌ Must wait

✅ Usually safe

⚠️ Depends on procedure

Immediate Comfort

✅ Hydrating base

❌ Often drying

✅ Usually comfortable

⚠️ May sting initially

Why It Works

Cellular Renewal Serum feeds your skin what it’s missing at the cellular level.

A French biotech serum — Swiss apple plant cell culture, a salmon-derived DNA polynucleotide complex, and Bloomage hyaluronic acid — designed to help support the appearance of firmer, smoother, more resilient-looking skin. Individual results may vary.

Clinical Proven Result

Renewal Support

PhytoCellTec™ Swiss apple cell culture, designed to support a youthful-looking complexion.

Firmness Support

Salmon-derived DNA helps support the appearance of firmer, more resilient-looking skin.

Skin Barrier Support

Helps maintain moisture retention and supports the appearance of skin firmness†

In a 28-day study of the active ingredient at the studied concentration, researchers observed increased firmness and dermal density. Individual results may vary

Read the Ingredient Science

Know More

What's Inside Each Bottle:Advanced Actives:

Advanced Actives:
• PhytoCellTec™ Malus Domestica - Swiss apple cell culture, designed to support a youthful-looking complexion
• Salmon-derived DNA polynucleotide complex — supports the appearance of firmness
• Hyaluronic Acid - deep, lasting hydration

Free From: Harsh acids, synthetic fragrances, parabens, sulfates

Simple Daily Application:

1. Apply to clean, dry skin (AM/PM both suitable)
2. Use 1-2 pumps on face and neck
3. Pat gently around eye contour if tolerated
4. Follow with moisturizer and SPF (AM essential)

Getting Started:
• Week 1: Once daily to assess tolerance
• Week 2+: Increase to twice daily as tolerated
• With actives: Alternate nights initially, keep routine simple

The Science Behind Advanced Renewal:

• Designed to support the skin's natural-looking renewal for a refreshed appearance
• Helps support the look of a firmer, smoother complexion
• Helps support a comforted, resilient-looking skin barrier

Our Advanced Formulation Promise

We believe that what you put into your body matters. Every ingredient, process, and standard we follow is driven by science, safety, and transparency.

PhytoCellTec™ Technology

Patented Swiss apple stem cell extract

Salmon-derived DNA polynucleotide complex

Same DNA fragments used in cosmetic dermatology

Stability Tested

Maintains potency throughout shelf life

Gender-Neutral Design

Effective for all skin types and preferences

Important Usage Information

External use only - Avoid direct eye contact

Patch test recommended for very sensitive skin types

Professional procedures: Only use after clinician clearance

Store cool and dry to maintain active ingredient stability

Discontinue if irritation occurs and consult dermatologist

How Our Four Actives Work Together

We believe that what you put into your body matters. Every ingredient, process, and standard we follow is driven by science, safety, and transparency.

Stem Cell Protection

PhytoCellTec™ maintains your skin's natural renewal capacity

Regeneration Signaling

Salmon-derived DNA complex, formulated to support the appearance of resilience

Barrier Support

Hyaluronic acid and antioxidants create optimal healing environment

Sustained Results

Unlike harsh actives, this approach builds lasting improvement

Blogs

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FAQ

Can I use this with acids or retinoids?

Start by alternating nights and keep the rest of your routine simple. The gentle formula is designed to layer well with other actives once your skin adapts.

Is it safe around the eye area?

Yes — pat a thin layer along the orbital bone if tolerated. The gentle formula is designed to help soften the look of fine lines around the eyes.

Can I use this after cosmetic procedures?

Only after clearance from your clinician. Many find it a comfortable choice for maintaining the look of results from professional treatments.

When will I see results?

Most users notice softer, more hydrated-looking skin within a couple of weeks, with visible improvement in the look of fine lines and firmness by weeks 3-6. Individual results may vary.