Sugar-freeVegan, all three30 gummies eachcGMPthird-party batch tested

THE COMPLETE CELLULAR RITUAL1st Place, Healthy Aging — Nutrition Industry Executive 2021 · Prix Galien UK 2026 nominee — the Q-Actin research

Your body doesn't age in one place. Why does your routine only cover one?

Three specialised formulas, one coordinated system — your joints, your cellular defence and your mineral floor. Every milligram printed. Every trial, and every gap, disclosed.

5human trials, all published

1dedicated cellular transporter

≥77%fulvic — three assay methods

0proprietary blends

60-day refund — opened or not, nothing to send back · Free US shipping · The File — every study — sent the moment you order

Joints — VFlex with Q-Actin® for everyday comfort & mobility
The mineral floor — Vioni+ with Ioniplex®, for everyday vitality and luminous-looking skin from within
Cellular defence — MitoV+ with MitoPrime®, the antioxidant your body built a transporter for
The full daily ritual — three gummies, one cellular foundation

Two in the morning. One before bed.

Morning

Vioni+ and MitoV+, with or without food.

Day

Nothing. There's no midday dose to forget.

Night

VFlex, about thirty minutes before bed.

The three VyVa canisters beside a shelf of all-in-one supplements

20 + 5 + 200 = 225 MG · THREE ACTIVES · ZERO OVERLAP

Three bottles isn't complexity. It's the refusal to dilute.

A capsule has a fixed volume — everything you add takes space from something else. That's why all-in-one formulas carry twenty ingredients at amounts no trial ever used. Fitting three actives into one capsule means cutting all three down until they fit. We made the opposite trade.

There's a part a capsule structurally cannot do, either: VFlex belongs at night, the other two in the morning — and no capsule is taken at two times of day. That isn't a preference; it's the arithmetic that decides the format.

225 mg total, nothing overlapping with anything else you take. One active per bottle, every dose printed — so you can tell what's doing something, and drop what isn't.

One System, Three Intercepts

Why these three? Because biology doesn't work in silos.

01 · The Structural Shield · Evening

VFlex

20 mg of Q-Actin® — the dose from a sponsor-funded, 180-day, double-blind head-to-head against 2,700 mg of glucosamine-chondroitin, run with no placebo arm. Measured against each group's own starting point, the Q-Actin group's improvement was more than double. A separate twelve-week trial, placebo-controlled and publicly funded, ran the same 20 mg in gummy form in the evening — the section below sets out exactly what it found and what it didn't. For the small movements you never thought about until they got harder: buttons, jar lids, the first ten minutes of the morning. Taken at night, the timing the trials used.

02 · The Cellular Retention Engine · Morning

MitoV+

5 mg of MitoPrime® L-ergothioneine — 100% pure L-isomer, naturally fermented, and GRAS-affirmed since 2018. Your body did not build a transporter for most of what you swallow. It built one for this: OCTN1, a carrier that exists specifically to pull ergothioneine into cells and hold it there. In laboratory work the compound eliminated reactive oxygen species up to thirty times more effectively than glutathione, and cut lipid peroxidation at roughly twice the rate of CoQ10 at the same concentration. Your own stores decline from early adulthood onward. This is the one you take to stop the floor moving.†

03 · The Mineral Floor · Morning

200 mg of Ioniplex® — over 65 major, minor and trace minerals in ionic form, at ≥77% fulvic acid, with the guaranteed composition published rather than summarised. Extracted under patent from mineraloid veins across North America at a facility in Goodyear, Arizona. In human cell work it bound cells at over ten times the signal of untreated controls and carried magnesium inside them — which is the entire argument for an ionic mineral, because a mineral you cannot absorb is a mineral you did not take. The cofactor foundation the other two depend on.†

Three gummies. Thirty seconds. Sugar-free and vegan, all three. 225 mg total — against the 6,000–12,000 mg of a typical scoop.

An open VyVa canister showing individually wrapped gummies

Inside the canister

Thirty days, individually wrapped.

One wrapped gummy per dose — no scoops, no measuring, nothing to keep in the fridge. Every active and its amount is printed on the panel.

JUDGED BY PEOPLE WHO ASSESS INGREDIENTS FOR A LIVING

The joint active in this box won its category — and the judges said the quiet part out loud.

The award Q-Actin® took 1st Place, Healthy Aging at the 2021 Nutrition Industry Executive awards — the trade's annual recognition of "the most cutting-edge and advanced natural branded nutritional ingredients backed by science." Judged on research, evidence and bioavailability; sustainability, traceability and certifications; consumer need; and what the panel calls the impressiveness factor.

What the judge said "The fact that it only requires a 20 mg dose and has demonstrated greater efficacy than a considerably higher dose of glucosamine/chondroitin makes Q-actin truly novel." — Gene Bruno, MS, MHS, RH(AHG), Vice President of Scientific and Regulatory Affairs, Twinlab Consolidation Corporation.

And the second judge "An interesting botanical," supported by "good human clinical studies demonstrating safety and benefits." — Cheryl Myers, Chief Science and Education Officer, EuroPharma Inc.

Why the dose is the story Twenty milligrams, against 2,700 mg of glucosamine-chondroitin in the head-to-head. The same category, two orders of magnitude apart. That ratio is the entire reason this fits in a gummy instead of a horse pill — and it is what the judging panel singled out.

How it is understood to work Q-Actin® is an iminosugar — a sugar ring in which a nitrogen atom replaces the oxygen. As described in the award citation, it acts on tumour necrosis factor alpha, an inflammatory cytokine whose overproduction raises the metalloproteinases associated with cartilage breakdown, and is understood to bind the CD44 hyaluronic acid receptor.†

Where most joint formulas stop Glucosamine, chondroitin, curcuminoids, collagen and eggshell membrane supply the building blocks for repair. The trade press puts it plainly: they do little to address the inflammation that often causes the damage in the first place. This is the other half of the problem.

1st Place, Healthy Aging category, Nutrition Industry Executive, October/November 2021. Judges' remarks quoted as published. Q-Actin® is a registered trademark of IminoTech, Inc., Carson City, Nevada. † These statements have not been evaluated by the Food and Drug Administration.

THE COMBINED PROOF BAR

Three actives. Three different kinds of evidence. We name which is which.

We don't lend one module's evidence to another, and we don't pretend a laboratory report is a journal paper. Here is exactly where each one stands — and all of it ships with the box.

Row	VFlex	MitoV+	Vioni+
Evidence tier	Five published human trials, one at our exact dose and format	GRAS-affirmed compound with a transporter your body already built	A controlled human study plus a laboratory dossier
Dose	20 mg Q-Actin®	5 mg MitoPrime®	200 mg Ioniplex®
What sits behind it	5 published papers — four placebo-controlled, one against an active comparator. One run in gummy form at our dose and timing, publicly funded	No trials on the branded material. Compound-level and transport research, plus GRAS affirmation in 2018	A six-week randomised, double-blind, placebo-controlled study — supplier-commissioned and unpublished — plus laboratory reports on absorption, mitochondrial metabolism, collagen and glycation
What we claim	A dose-matched clinical outcome	Purity, and a dedicated transporter	An absorbable mineral foundation, with the dossier attached
Sent with your order	All five papers, in full	Purity specification sheet and GRAS notice number	Assay certificate, the six-week study report and the laboratory reports

No study has tested these three together as a combined formula — they share a moment in your day and a shared target, not a proven synergy.

THE TRIAL AT OUR DOSE, OUR FORMAT, OUR TIMING

One of the five was run on gummies, at 20 mg, in the evening — and paid for with public money.

The paper Lloyd AJ, Nash RJ, et al. Frontiers in Nutrition 2025;12:1563999. Registered ISRCTN28705061 and NCT05878847. Read the full paper →

Design Twelve weeks, randomised, double-blind, against matched placebo gummies. 56 participants randomised, 47 started. Healthy adults aged 50 to 78.

Who paid for it The Welsh Government Covid Recovery Challenge Fund and Innovate UK Better Food for All (10068218). Public money — not the ingredient supplier.

Dose and format 20 mg a day, as two 10 mg gummies, taken in the evening before bed. The same dose, the same format and the same timing as VFlex.

What the authors concluded Improved sleep quality and finger dexterity. Dexterity on the Nine-Hole Peg Test: significant in the Q-Actin group at twelve weeks (p = 0.011) and between weeks six and twelve (p = 0.007), while the placebo group did not change at any timepoint. Sleep on two lines of evidence — elevated melatonin derivatives in urine, confirmed by LC-MS/MS fragmentation, alongside self-reported improvement on the Pittsburgh Sleep Quality Index.

What it did not show Grip strength improved in both groups and did not separate — the authors attribute that to a placebo or learning effect from repeated testing. The total PSQI sleep score did not reach significance; the component that moved was subjective sleep quality at six weeks (p = 0.020).

The authors' own limitations, in their words: the sample was relatively small, self-reported sleep measures such as the PSQI may be subject to bias, and future studies should incorporate objective monitoring such as actigraphy or polysomnography. We print those beside the result, because a finding without its limits isn't evidence — it's advertising.

THE PART THE MINERAL AISLE NEVER SHOWS YOU

Vioni+ has no journal-published trial. It has something almost no mineral supplement has: a dossier, and we send all of it.

A controlled human study Six weeks, randomised, double-blind and placebo-controlled, in three groups of healthy women. Nail growth, measured instrumentally by digital photography, ran 142% and 141% against 129% in the control group. Skin texture improved 33% from baseline at six weeks; hair condition 14%. Conducted by International Research Services, report 3411BK0609.†

Absorption, measured In human cell work, Ioniplex® bound cells at over ten times the fluorescence signal of untreated controls, then delivered magnesium inside them. For a mineral, that is the whole argument — a mineral you cannot absorb is a mineral you did not take.

Mitochondrial metabolism Tested head to head against two leading commercial energy drinks, Ioniplex® produced the greatest stimulation of mitochondrial metabolic activity among the materials tested — over 50% at certain concentrations. Gene-expression profiling across more than 20,000 genes showed stimulation of genes involved in aerobic energy production.†

Collagen Repeatedly stimulated Type I collagen in human dermal fibroblasts — averaging around 30%, and as much as quadruple depending on the cell line used.†

Glycation Reduced advanced glycation end-products by up to 50% in a dose-dependent manner, comparable with aminoguanidine — and patented on that basis, US Patent 8,927,031.†

Where it comes from Mineraloid veins across North America, extracted under a separate patent (US 9,044,417) at a facility in Goodyear, Arizona. Over 65 major, minor and trace minerals, with the guaranteed composition published in full rather than summarised as a count.

These are the ingredient maker's own laboratory and clinical reports rather than peer-reviewed journal papers, and we label them that way on purpose — you should know the difference, and you should be the one to weigh it. Every report listed here ships with your order. † These statements have not been evaluated by the Food and Drug Administration.

IF YOU ALREADY TAKE TURMERIC

You already pay extra for absorption. This is the same idea — and it's already in the box.

Turmeric on its own Turmeric with Ioniplex®Absorbed at three hours 8.1% 9.5% — a 17.5% increase, p = 0.026Absorbed at five hours 9.1% 10.5% — a 15.9% increase, p = 0.003What was tested Turmeric alone, crossing the membrane. A 1:1 combination with Ioniplex®, run in triplicate on the Millipore PAMPA model — the standard laboratory stand-in for passive intestinal absorption.Why it matters Turmeric is famously hard to absorb. That single fact is why the aisle sells piperine, phytosomes and oil carriers at a premium — you are already paying for absorption. The report's own conclusion: a statistically significant increase, "demonstrating its potential to enhance the passive intestinal absorption of nutrients."What this is not — A laboratory membrane model, not a human absorption study. We are not claiming a result in your body — we are telling you what the carrier did in the test, and sending you the report so you can read it yourself.

Vioni+ is a morning dose for exactly this reason: the mineral floor is what the rest of your routine stands on.

START THE RITUAL — $98.90

60-day refund — opened or not, nothing to send back.

A scoop of a many-ingredient greens blend

THE OTHER DIRECTION

Seventy-five ingredients. Name three, and how much of each.

That's the scoop most people start their morning with. It isn't a bad product — it's a promise that can't be checked. Everything in a one-scoop formula shares the same space, the same flavour and the same price, so the amounts get small: small enough that most of them exist to be printed on the label rather than to do anything. And because it's sold as a blend, you're not told which amounts.

Here's the part nobody says out loud: if it works for you, you won't know what worked. And if it stops working, you won't know what to change. Not because they're hiding something — because a 75-ingredient blend can't be diagnosed. Not by you, and not by them.

We went the other way. Three actives, one in each bottle: 20 mg, 5 mg, 200 mg, printed where you can read them. If something changes, you know which bottle did it. If something doesn't, you know what to drop. 225 milligrams you can name, instead of eight grams you can't.

IF YOU'VE LOOKED AT SHILAJIT

You bought shilajit and couldn't find a strength printed anywhere on the label.

Raw shilajit resin Vioni+Strength on the label Usually nowhere on the jar. A mountain on the front and a spoon to guess with. 200 mg of Ioniplex®, printed on the panel.Fulvic acid Typically 15–20% of raw resin — and the number moves depending on which assay produced it. ≥77% fulvic acid.Is the method named? Rarely. Without the method, the percentage is an artefact rather than a fact. Cross-checked by three separate laboratory methods, all named. We publish the method, not just the number.Batch to batch Varies with altitude, season and supplier. The same 200 mg in every gummy, every batch.Heavy metals A documented risk in the category. Batch-screened. The certificate for your batch ships with the order.Provenance A mountain range on the label, and rarely a site. Mineraloid veins across North America, extracted under patent in Goodyear, Arizona. We name the site.Format A spoon of resin. One tamarind gummy. No spoon, no tar.

The minerals are the floor, not the whole building — which is why Vioni+ is one of three rather than something sold on its own.

The File

Most brands send a discount code. We send the papers.

Every Q-Actin® paper is public and linked below — read them before you buy, or let them arrive with the box. The mineral dossier, the assays and your batch certificate come with the order.

Lloyd 2025 — twelve weeks, double-blind, placebo-controlled, run on gummies at 20 mg in the evening. Publicly funded. Read the paper →
Nash 2018 — 180 days against 2,700 mg of glucosamine-chondroitin. An active comparator, with no placebo arm, and we say so. Read the paper →
Nash 2023 — placebo-controlled, on parameters linked to moderate osteoarthritis. Read the paper →
Hausenblas 2025 — mild to moderate joint pain. Randomised, double-blind, placebo-controlled. Read the paper →
Hausenblas 2025 — mood, anxiety and sleep quality. Randomised, double-blind, placebo-controlled; the group-by-time interaction was not significant and the authors advise caution. We send it anyway. Read the paper →
The Ioniplex® six-week randomised, double-blind, placebo-controlled study on nail, hair and skin condition (report 3411BK0609), plus the laboratory reports on absorption, mitochondrial metabolism, collagen, glycation and the turmeric permeation test.
The Ioniplex® assay certificate for your batch — ≥77% fulvic acid, all three methods named — and the published guaranteed mineral composition.
The MitoPrime® purity specification, 100% pure L-isomer, and its 2018 GRAS notice. No clinical trials on the branded material, and we don't imply any.

Every paper · Every assay · Every batch · Sent on order

Clinical study papers, notebook, and coffee on a workspace surface

Things we decided not to do.

No proprietary blends. One active per bottle, dose printed.
No "doctor approved" badge. We don't have one, and neither do the brands using it.
No before-and-after photographs. Shot in different light, they prove nothing.
No countdown timers, no fake scarcity. The price is the price.
No reviews yet. We're new. When we have real customers we'll publish what they actually said, including the unflattering parts.

Everything on this page can be checked. That's the entire pitch.

FAQ

Why three bottles instead of one capsule?: One is taken at night and two in the morning — no single capsule can be taken at two times of day.
Is there clinical evidence?: For Q-Actin, yes — five published human trials. Four are placebo-controlled; one is a 180-day head-to-head against glucosamine-chondroitin with no placebo arm, and we label it that way. One of the five was run at our dose, in our format, in the evening, and was publicly funded. For Ioniplex there is a six-week randomised, double-blind, placebo-controlled study on nail, hair and skin condition — supplier-commissioned and unpublished, so we send you the report rather than a headline. For MitoPrime, research at compound and transporter level, GRAS-affirmed in 2018, with no trials on the branded material.
When will I notice something?: No date. Anyone who gives you one is guessing.
Can I cancel?: Any time, two clicks. No call, no email, no retention script.
Who is this actually for?: People past thirty-five who are done buying volume — and anyone with a cabinet of half-finished bottles they can't account for. The whole design is so you can tell which bottle did something, and which one to drop.
I already take turmeric. Does this replace it?: No — and we wouldn't tell you to drop it. In a laboratory membrane model, turmeric combined 1:1 with Ioniplex crossed at a statistically significant 17.5% higher rate than turmeric alone. That is a test, not your gut, and we say so. But it is the reason the mineral goes in the morning, with the rest of what you take.

For the first signs
of slowing down.

THE COMPLETE CELLULAR RITUAL

A man pausing in a stone doorway in soft daylight

THE GUARANTEE

Sixty days. Then decide.

If it isn't for you, tell us and we'll refund it. Keep the product — there's nothing to send back. Sixty days is a refund window, not a results window.

60-day refund — opened or not, nothing to send back · Free US shipping · The File — every study — sent the moment you order

COMPLETE THE SYSTEM

Where this ritual leads.

The Defence RitualMitoV+ and Cellular Clarity — one you take, one you apply, both in the morning.One price, from day one until you cancel.Subscribed: $92.15/month~~$128.00~~$102.40 one-time Save $10.25 every monthSEE THE RITUAL →

The Foundation RitualVioni+ in the morning, Cellular Renewal at night — the simplest way in.One price, from day one until you cancel.Subscribed: $102.95/month~~$143.00~~$114.40 one-time Save $11.45 every monthSEE THE RITUAL →

Bare DuoClarity in the morning, Renewal at night — the two-serum routine.One price, from day one until you cancel.Subscribed: $120.95/month~~$168.00~~$134.40 one-time Save $13.45 every monthSEE THE RITUAL →

The Journal

ALL ARTICLES

Evidence What "Clinically Studied" Actually Means on a Supplement Label (and How Most Brands Bend It)

VFlex Q-Actin® vs Glucosamine: A Side-by-Side Look at the Evidence Shop VFlex →

MitoV+ L-Ergothioneine: The Longevity Compound Behind MitoV+ Shop MitoV+ →

Vioni+ What Shilajit Was Trying to Be: The Case for Standardized Fulvic Minerals Shop Vioni+ →

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Individual results vary. Consult your physician before beginning any supplement. Q-Actin® is a registered trademark of IminoTech, Inc., USA. MitoPrime® is a registered trademark of NNB Nutrition. Ioniplex® is a registered trademark of Mineral BioSciences USA. Laboratory and supplier-commissioned reports are identified as such wherever they appear on this page.